A systematic review of population-based studies on lipid profiles in latin america and the caribbean

Carrillo-Larco R.M.; Benites-Moya C.J.; Anza-Ramirez C.; Albitres-Flores L.; Sánchez-Velazco D.; Pacheco-Barrios N.; Bernabe-Ortiz A. · eLife (2020) · DOI: 10.7554/elife.57980

Resumen

We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Cholesterol [HDL-C; 84 studies; 121,282 people], LDL-Cholesterol [LDL-C; 61 studies; 86,854 people], and triglycerides [TG; 84 studies; 121,009 people]) levels and prevalences were laboratory-based. We used Scopus, LILACS, Embase, Medline and Global Health; studies were from 1964 to 2016. Pooled means and prevalences were estimated for lipid biomarkers from ≥2005. The pooled means (mg/dl) were 193 for TC, 120 for LDL-C, 47 for HDL-C, and 139 for TG; no strong trends. The pooled prevalence estimates were 21% for high TC, 20% for high LDL-C, 48% for low HDL-C, and 21% for high TG; no strong trends. These results may help strengthen programs for dyslipidaemias prevention/management in LAC. © Carrillo-Larco et al.

Instituciones: Universidad Peruana Cayetano Heredia; Universidad Nacional de Trujillo; Universidad Científica del Sur; Universidad Católica Los Ángeles de Chimbote