A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon

Falconi-Agapito F.; Selhorst P.; Merino X.; Torres F.; Michiels J.; Fernandez C.; Talledo M.; Ariën K.K. · International Journal of Infectious Diseases (2020) · DOI: 10.1016/j.ijid.2020.04.087

Resumen

We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant with two novel mutations (I379T and V484I) located in domain III of DENV2-E.

Instituciones: Universidad Peruana Cayetano Heredia