A giant parathyroid cyst causing primary hyperparathyroidism in a pregnant woman: Case report and literature review

Paz-Ibarra J.; Concepción-Zavaleta M.J.; Coronado-Arroyo J.C.; Quiroz-Aldave J.E.; Pino-Godoy P.; Díaz-Lazo H.; Chávez-Torres H.; Carrión-Cabezas P.; Somocurcio-Peralta J. · Obstetric Medicine (2025) · DOI: 10.1177/1753495x241249201

Resumen

Introduction: Primary hyperparathyroidism (PHPT) during pregnancy is rare, with the commonest cause being parathyroid adenoma. Parathyroid cysts represent 0.5% of parathyroid lesions. The diagnosis of PHPT requires elevated levels of calcium, along with elevated or non-suppressed parathormone levels. Conservative treatment prevails unless hypercalcemia persists. Case: A 33-week pregnant woman with preeclampsia and a cervical tumor was diagnosed with PHPT due to a functioning cystic adenoma. She underwent a caesarean section at 36 weeks, delivering a low-birthweight live newborn. Six months post-caesarean section the patient underwent right inferior parathyroidectomy and right hemithyroidectomy, with histopathological findings consistent with a giant cyst parathyroid adenoma. At review three months. after surgery, there are no signs of the persistence of the disease. Conclusion: A giant functional parathyroid cyst causing PHPT and being identified in pregnancy is exceedingly rare. It is crucial to have a timely multidisciplinary diagnosis and management to avoid maternal and fetal complications. © The Author(s) 2024.

Instituciones: Universidad Nacional Mayor de San Marcos; Universidad Científica del Sur